Analysis of 31-year-old patient with SYNGAP1 gene defect points to importance of variants in broader splice regions and reveals developmental trajectory of SYNGAP1-associated phenotype: case report

Abstract Background Whole exome sequencing is a powerful tool for the analysis of genetically heterogeneous conditions.The prioritization of variants identified often focuses on nonsense, frameshift and canonical splice site mutations, and highly deleterious missense variants, although other defects can also play a role.The definition of the phenot

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Emergence of new types of Theileria orientalis in Australian cattle and possible cause of theileriosis outbreaks

Abstract Theileria parasites cause a benign infection of cattle in parts of Australia where they are endemic, but have, in recent years, been suspected of being responsible for a number of outbreaks of disease in cattle near the coast of New South Wales.The objective of this study was to identify and characterize the species of Theileria in cattle

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The Ideology of Climate Change Denial in the United States

The concerted effort to discredit the scientific consensus over man-made global warming has been B Complex continuing for two decades in the United States, and shows no sign of weakening.It is very often described as an attempt on the part of corporate America, most notably the fossil fuel industries, to hinder governmental regulations on their act

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